Portfolio
Pipeline
Abbreviations: HGF: hepatocyte Growth Factor, BDNF: brain derived neurotrophic factor, AD: Alzheimer’s Disease, PD: Parkinson’s Disease, NASH: non-alcoholic steatohepatitis, NHP: non-human primate
Portfolio Creation
We will shape our portfolio through a variety of approaches enabled by LassoGraft Technology®, including
“Plug & play” capability: Connect and function immediately
- Addition of second/third functions to existing antibodies
- Granting blood-brain barrier (BBB) permeability
Designing molecules considering topology in three dimensions
- Creation of agonists with controlled 3D conformation
Giving directionality to gene therapy
- Central Nervous System (CNS)/cell-directed AAV/Lipid Nano Particle (LNP)
Application to modalities other than immunoglobulins
- Addition of functions to bioactive proteins such as cytokines